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Thelate1800sbecameknownasthegoldenageofmicrobiology.Advancescamerapidlyandlifewasdramaticallyimproved.Buttheadvancesthathavecontinuedtobemadeduringthetwentiethcenturyhavebeennolessstriking.Let’slookbrieflyatfourkeyareas:chemotherapy,immunology,virology,an...[继续阅读]
Thepresentthemeissue,whichhighlightsthepharmaceuticalperspectiveonpolymorphism,followsanearlierthemeissueon“CharacterizationoftheSolidState”,whichhighlightsthefundamentalaspectsofthisphenomenon.Currentresearchareasofgreatestfundamentalinterestare:(a)deter...[继续阅读]
Danshen,thedriedrootofSalviamiltiorrhiza(Fam.Labiatae),isacommonlyusedtraditionalChinesemedicine(TCM)forimprovingbodyfunction(e.g.,promotingcirculationandimprovingbloodflow).Inaddition,ithasbeenusedforthetreatmentofcardiovasculardiseasessuchascoronaryhear...[继续阅读]
DESCRIPTIONPantethineisthedisulfidedimerofpantetheine,the4’-phosphatederivativeofwhichisanintermediateintheconversionoftheBvitaminpantothenicacidtocoenzymeA(seePantothenicAcid).Pantethineisfoundnaturallyinsmallquantitiesinmostformsoflife,andtherefore,info...[继续阅读]
Yinandyang,whichcomesfromancientChinesephilosophy,isageneraltermfortwooppositesidesofinterrelatedthingsorphenomenainthenature.Atfirst,theirconnotationswerequitesimple,referringtothetwooppositesidesofanobject.Thesidefacingthesunisyangandthereversesideisyin...[继续阅读]
ChemicalConstituentsThechemicalconstituentsofDanshenhavebeenstudiedsincetheearly1930s.However,theseearlystudiesmainlyfocusedonthelipophiliccompounds.Recentstudieshavefocusedmoreonhydrophiliccompounds,andatleast50componentshavebeenisolatedandidentifiedfrom...[继续阅读]
RATIONALEFacilitiesmustoperatetomeetenvironmentaldesigncriteriainordertoprotectproductfromcontaminationordeterioration.Routinemonitoringmustbeperformedtoensurethattherequiredstandardsareachieved.PURPOSEThisguidelineprovidesaframeworkforestablishingmicrobi...[继续阅读]
GLUCOVANCEⓇRxonly(GlyburideandMetforminHClTablets)1.25mg/250mgDESCRIPTIONGLUCOVANCEⓇ(GlyburideandMetforminHClTablets)containstwooralantihyperglycemicdrugsusedinthemanagementoftype2diabetes,glyburideandmetforminhydrochloride.Glyburideisanoralan...[继续阅读]
IntroductionInthischapterthetopicisthetechniquesforpreparingpharmaceuticalsamplesforanalysis.Samplepreparationofpharmaceuticalproductsaswellasbiologicalsamplesisdiscussed.Thescopeofthischapterincludesonlysamplepreparationforchromatographicanalysisinwhicht...[继续阅读]
Pharmaceuticsisamultidisciplinaryappliedscienceconcernedwithdeliveringandmaintainingappropriatedrugconcentrationsattargetsitesinthebodyforappropriatetimes,thusalleviatingdiseasebyoptimizingdrugeffectsovertime.Itincludesdrugproducttechnology,biopharmaceuti...[继续阅读]
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