当前位置:首页 > 医学文档 > 呼吸系统 > 正文

Clinicalasthmaphenotyping:Atrialforbridginggapsinasthmamanagement

WorldJournalofClinicalPediatrics 页数: 6 2015-05-08
摘要: Asthmaisacommondiseaseaffectingmillionsofpeopleworldwideandexertinganenormousstrainonhealthresourcesinmanycountries.Evidenceisincreasingthatasthmaisunlikelytobeasinglediseasebutratheraseriesofcomplex,overlappingindividualdiseasesorphenotypes,eachdefinedbyitsuniqueinteractionbetweengeneticandenvironmentalfactors.Asthmaphenotypeswereinitiallyfocusedoncombinationsofclinicalcharacteristics,buttheyarenowevolvingtolinkpathophysiologicalmechanismtosubtypesofasthma.Bettercharacterizationofthosephenotypesisexpectedtobemostusefulforallocatingasthmatherapies.Thisarticlereviewsdifferentpublishedresearchesintermsofunbiasedapproachestophenotypeasthmaandemphasizeshowthephenotypingexerciseisanimportantsteptowardsproperasthmatreatment.Itisstructuredintothreesections;theheterogeneityofasthma,theimpactofasthmaheterogeneityonasthmamanagementanddifferenttrialsforphenotypingasthma. ... (共6页)

开通会员,享受整站包年服务
说明: 本文档由创作者上传发布,版权归属创作者。若内容存在侵权,请点击申诉举报