知识贝壳
知识贝壳
所属栏目：精神病学
【日期】：2019-07-18
【关键词】：type 2 diabetes;insulin/insulin-like growth factor-1;insulin receptor substrate;Alzheimeru0027s disease;aging;serine phosphorylation;metformin;neuroprotective effects;high-fat-diet
【摘要】：Type 2 diabetes—associated with impaired insulin/insulin-like growth factor-1(IGF1) signaling(IIS)—is a risk factor for cognitive impairment and dementia including Alzheimeru0027s disease(AD). T...