Bone Research(2025年04期)
骨研究(英文版)

目 录

• Current cutting-edge omics techniques on musculoskeletal tissues and diseases
• Pathophysiology of Myopenia in rheumatoid arthritis
• Cellular senescence and other age-related mechanisms in skeletal diseases
• Nucleic acid aptamers in orthopedic diseases:promising therapeutic agents for bone disorders
• M2 macrophages-derived exosomes for osteonecrosis of femoral head treatment:modulating neutrophil extracellular traps formation and endothelial phenotype transition
• Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies
• KIAA1199(CEMIP) regulates adipogenesis and whole-body energy metabolism
• NELL2, a novel osteoinductive factor, regulates osteoblast differentiation and bone homeostasis through fibronectin 1/integrin-mediated FAK/AKT signaling
• SPI1 activates mitochondrial unfolded response signaling to inhibit chondrocyte senescence and relieves osteoarthritis
• Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice
• RUNX2 is essential for maintaining synchondrosis chondrocytes and cranial base growth
• Age- and sex-specific deterioration on bone and osteocyte lacuno-canalicular network in a mouse model of premature aging
• Synovial fibroblast derived small extracellular vesicles miRNA15-29148 promotes articular chondrocyte apoptosis in rheumatoid arthritis
• AIDS patients suffer higher risk of advanced knee osteoarthritis progression due to lopinavir-induced Zmpste24 inhibition
• Mouse model of anti-RANKL discontinuation reveals reduced bone mass and quality through disruption of bone remodeling
• IGF2BP3-mediated m~6A modification of RASGRF1 promoting joint injury in rheumatoid arthritis
• Chaperone-mediated autophagy directs a dual mechanism to balance premature senescence and senolysis to prevent intervertebral disc degeneration